Titre :
  • The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis.
Auteur : Ohara-Imaizumi, M. ; Cardozo, Alessandra K ; Kikuta, T. ; Eizirik, Decio L. ; Nagamatsu, S.
Informations sur la publication : The Journal of biological chemistry, 279, 40, (page 41271-41274)
Statut de publication : Publié, 2004
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Cells, Cultured
Cytokines -- pharmacology
Exocytosis -- drug effects
Insulin -- metabolism
Interleukin-1 -- pharmacology
Islets of Langerhans -- metabolism
Male
Membrane Fusion -- drug effects
Membrane Proteins -- analysis
Membrane Proteins -- genetics
Microscopy, Interference
Nerve Tissue Proteins -- analysis
Nerve Tissue Proteins -- genetics
RNA, Messenger -- biosynthesis
Rats
Rats, Wistar
Secretory Vesicles -- metabolism
Synaptosomal-Associated Protein 25
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0021-9258 
info:doi/10.1074/jbc.C400360200
info:pii/C400360200
info:pmid/15319424