Titre :
  • High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB.
Auteur : Elouil, H. ; Cardozo, Alessandra K ; Eizirik, Decio L. ; Henquin, Jean Claude ; Jonas, John Joseph
Informations sur la publication : Diabetologia, 48, 3, (page 496-505)
Statut de publication : Publié, 2005
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Antioxidant
Glucose toxicity
NFκB
Oxidative stress
Pancreatic beta cell
Mots-clés MeSH : Animals
Glucose -- pharmacology
Heme Oxygenase (Decyclizing) -- genetics
Heme Oxygenase-1
Hydrogen Peroxide -- pharmacology
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
MAP Kinase Signaling System -- drug effects
MAP Kinase Signaling System -- physiology
NF-kappa B -- metabolism
Proto-Oncogene Proteins c-myc -- genetics
RNA, Messenger -- drug effects
RNA, Messenger -- genetics
Rats
Transcription, Genetic -- drug effects
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-004-1664-4
info:pmid/15739117