Titre :
  • Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study.
Auteur : Massat, Isabelle ; Souery, Daniel ; Del-Favero, Jurgen ; Nothen, M ; Blackwood, Douglas Hr ; Muir, W ; Kaneva, Radka Petrova ; Serretti, A ; Lorenzi, C ; Rietschel, Marcella ; Milanova, V ; Papadimitriou, George ; Dikeos, Dimitris ; Van Broekhoven, C ; Mendlewicz, Julien
Informations sur la publication : Molecular psychiatry, 10, 6, (page 598-605)
Statut de publication : Publié, 2005-06
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Age at onset
Association study
Bipolar disorder
Candidate genes
Catecholamine neurotransmission
COMT gene
Major depressive disorder
Mots-clés MeSH : Age Factors
Amino Acid Substitution -- genetics
Bipolar Disorder -- enzymology
Bipolar Disorder -- genetics
Case-Control Studies
Catechol O-Methyltransferase -- genetics
Depressive Disorder, Major -- enzymology
Depressive Disorder, Major -- genetics
Europe
Female
Genetic Predisposition to Disease -- genetics
Humans
Linkage Disequilibrium -- genetics
Male
Polymorphism, Single Nucleotide -- genetics
Reference Values
Risk Factors
Note : Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1359-4184 
info:doi/10.1038/sj.mp.4001615
info:pii/4001615
info:pmid/15583702