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cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.

par Christensen, Anne E;Selheim, Frode;de Rooij, Johan;Dremier, Sarah ;Schwede, Frank;Dao, Khanh K;Martinez, Aurora;Maenhaut, Carine ;Bos, Johannes L;Genieser, H-G;Døskeland, Stein O
Référence The Journal of biological chemistry, 278, 37, page (35394-35402)
Publication Publié, 2003-09

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Titre:	cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.
Auteur:	Christensen, Anne E; Selheim, Frode; de Rooij, Johan; Dremier, Sarah; Schwede, Frank; Dao, Khanh K; Martinez, Aurora; Maenhaut, Carine; Bos, Johannes L; Genieser, H-G; Døskeland, Stein O
Informations sur la publication:	The Journal of biological chemistry, 278, 37, page (35394-35402)
Statut de publication:	Publié, 2003-09
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Cyclic AMP -- analogs & derivatives
	Cyclic AMP -- metabolism
	Cyclic AMP-Dependent Protein Kinases -- metabolism
	Cyclic GMP -- analogs & derivatives
	Cyclic GMP -- metabolism
	Enzyme Activation
	Guanine Nucleotide Exchange Factors -- chemistry
	Guanine Nucleotide Exchange Factors -- metabolism
	Kinetics
	Models, Molecular
	Peptide Fragments -- chemistry
	Peptide Fragments -- metabolism
	Protein Conformation
	Recombinant Fusion Proteins -- metabolism
	Substrate Specificity
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M302179200
	info:pii/M302179200
	info:scp/0041315574
	info:pmid/12819211
	VX-003771