Titre :
  • 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
Auteur : Megalizzi, Véronique ; Mathieu, Véronique ; Mijatovic, Tatjana ; Gailly, Philippe ; Debeir, Olivier ; De Nève, Nancy ; Van Damme, Marc ; Bontempi, Gianluca ; Haibe-Kains, Benjamin ; Decaestecker, Christine ; Kondo, Yasuko ; Kiss, Robert ; Lefranc, Florence
Informations sur la publication : Neoplasia (New York, N.Y.), 9, 5, (page 358-369)
Statut de publication : Publié, 2007-05
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Actins -- chemistry
Animals
Antineoplastic Agents -- pharmacology
Apoptosis -- drug effects
Autophagy -- drug effects
Benzamides -- pharmacology
Calcium -- metabolism
Cell Line, Tumor
Cell Movement -- drug effects
Endoplasmic Reticulum -- drug effects
Female
Glioblastoma -- drug therapy
Glioblastoma -- pathology
Guanine Nucleotide Dissociation Inhibitors -- physiology
Humans
Mice
Neoplasm Transplantation
Piperidines -- pharmacology
Receptors, sigma -- agonists
Receptors, sigma -- physiology
Transplantation, Heterologous
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1476-5586 
info:pmid/17534441
info:pmcid/PMC1877975