Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents.

Ingrassia, Laurent; Lefranc, Florence; Mathieu, Véronique; Darro, Francis; Kiss, Robert

doi:doi/10.1593/tlo.08100

Recherche avancée | Historique de recherche Mon DI-fusion | À propos de DI-fusion | Contact |

Citer

Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents.

par Ingrassia, Laurent

;Lefranc, Florence

;Mathieu, Véronique

;Darro, Francis ;Kiss, Robert

Référence Translational Oncology, 1, 1, page (1-13)
Publication Publié, 2008-03

Article révisé par les pairs

Résumé :

This review covers the isolation, total synthesis, biologic activity, and more particularly the in vitro and in vivo antitumor activities of naturally occurring isocarbostyril alkaloids from the Amaryllidaceae family. Starting from these natural products, new derivatives have been synthesized to explore structure-activity relationships within the chemical class and to obtain potential candidates for preclinical development. This approach appears to be capable of providing novel promising anticancer agents.

Documents en relation

DI-fusion

Cancer patients' behavior towards natural health products
par Schils, Audrey , Souard, Florence , Pochet, Stéphanie , Mathieu, Véronique , De Vriese, Carine
Publication 2023-07-06
Cancer patients' behavior towards natural health products
par Schils, Audrey , Souard, Florence , Pochet, Stéphanie , Mathieu, Véronique , De Vriese, Carine
Publication 2023-07-06
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
par Moris, Victoria , Bruneau, Lucie , Berthe, Jérémy , Heuskin, Anne-Catherine , Penninckx, Sébastien , Ritter, Sylvia , Weber, Uli , Durante, Marco , Danchin, Etienne E.G.J. , Hespeels, Boris , Doninck, Karine Van
Publication 2024-12
ASO Author Reflections: Histological Growth Patterns of Colorectal Peritoneal Metastases Significantly Affect Prognosis in Patients Presenting for Curative-Intent Cytoreductive Surgery.
par El Asmar, Antoine , Kamdem, Leonel , Khaled, Charif , Liberale, Gabriel
Publication 2024-03
Engineered Wnt7a ligands rescue blood–brain barrier and cognitive deficits in a COVID-19 mouse model
par Trevino, Troy , Fogel, Avital , Otkiran, Guliz , Niladhuri, Seshadri , Sanborn, Mark , Class, Jacob , Almousawi, Ali , Vanhollebeke, Benoît , Tai, Leon M , Rehman, Jalees , Richner, Justin M , Lutz, Sarah E
Publication 2024-02-01

Référencement	Visibilité	Pérennité	Facilité
Les publications encodées constituent la bibliographie académique de l'Université.	Les documents déposés sont indexés par les moteurs de recherche (Google Scholar,…).	Les documents déposés en open-access sont archivés au sein du réseau de préservation SAFE-PLN (www.safepln.org).	Les listes de publications sont compatibles avec le CV-ULB, le FNRS et accessibles sur le web.