Titre :
  • Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis.
Auteur : Gurzov, Esteban Nicolas ; Ortis, Fernanda ; Andrade Da Cunha, Daniel ; Gosset, Geoffrey ; Li, M ; Cardozo, Alessandra K ; Eizirik, Decio L.
Informations sur la publication : Cell death and differentiation, 16, 11, (page 1539-1550)
Statut de publication : Publié, 2009
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Apoptosis
Apoptosis Regulatory Proteins -- metabolism
Cytochromes c -- metabolism
Endoplasmic Reticulum -- metabolism
Insulin-Secreting Cells -- cytology
Insulin-Secreting Cells -- metabolism
Interferon-gamma -- pharmacology
Interleukin-1beta -- pharmacology
JNK Mitogen-Activated Protein Kinases -- metabolism
Neuropeptides -- metabolism
RNA, Small Interfering -- metabolism
Rats
Rats, Wistar
Signal Transduction
Up-Regulation
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1350-9047 
info:doi/10.1038/cdd.2009.99
info:pii/cdd200999
info:pmid/19629134