Titre:
  • Expression of TNF-alpha by herpes simplex virus-infected macrophages is regulated by a dual mechanism: transcriptional regulation by NF-kappa B and activating transcription factor 2/Jun and translational regulation through the AU-rich region of the 3' untranslated region.
Auteur:Paludan, S R; Ellermann-Eriksen, S; Kruys, Véronique; Mogensen, S C
Informations sur la publication:The Journal of immunology, 167, 4, page (2202-2208)
Statut de publication:Publié, 2001-08
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:3' Untranslated Regions -- physiology
Activating Transcription Factor 2
Animals
Binding Sites -- genetics
Binding Sites -- immunology
Cells, Cultured
Cyclic AMP Response Element-Binding Protein -- genetics
Cyclic AMP Response Element-Binding Protein -- metabolism
Cyclic AMP Response Element-Binding Protein -- physiology
DNA-Binding Proteins -- biosynthesis
DNA-Binding Proteins -- genetics
Dinucleotide Repeats -- physiology
Female
Herpesvirus 2, Human -- immunology
I-kappa B Proteins
Interferon-gamma -- pharmacology
Macrophage Activation -- genetics
Macrophage Activation -- immunology
Macrophages, Peritoneal -- immunology
Macrophages, Peritoneal -- metabolism
Macrophages, Peritoneal -- virology
Mice
Mice, Inbred C57BL
Mutation
NF-kappa B -- antagonists & inhibitors
NF-kappa B -- genetics
NF-kappa B -- physiology
Promoter Regions, Genetic -- immunology
Proto-Oncogene Proteins c-jun -- physiology
RNA, Messenger -- antagonists & inhibitors
RNA, Messenger -- biosynthesis
Transcription Factors -- genetics
Transcription Factors -- metabolism
Transcription Factors -- physiology
Transcriptional Activation -- physiology
Transfection
Tumor Necrosis Factor-alpha -- antagonists & inhibitors
Tumor Necrosis Factor-alpha -- biosynthesis
Tumor Necrosis Factor-alpha -- genetics
Tumor Necrosis Factor-alpha -- secretion
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-1767
info:pmid/11490006