Titre:
  • Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1-binding sites.
Auteur:Goriely, Stanislas; Demonte, Dominique; Nizet, Séverine; De Wit, Dominique; Willems, Fabienne; Goldman, Michel; Van Lint, Carine
Informations sur la publication:Blood, 101, 12, page (4894-4902)
Statut de publication:Publié, 2003
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Base Sequence
Binding Sites
Cell Line
DNA -- chemistry
DNA -- metabolism
Dendritic Cells -- ultrastructure
Deoxyribonuclease EcoRI -- metabolism
Deoxyribonuclease I -- metabolism
Gene Expression Regulation -- drug effects
Humans
Interferon-gamma -- pharmacology
Interleukin-12 -- genetics
Lipopolysaccharides -- pharmacology
Luciferases -- genetics
Micrococcal Nuclease -- metabolism
Molecular Sequence Data
Monocytes -- ultrastructure
Nucleosomes -- chemistry
Nucleosomes -- ultrastructure
Promoter Regions, Genetic -- genetics
RNA, Messenger -- biosynthesis
Reverse Transcriptase Polymerase Chain Reaction
Sp1 Transcription Factor -- metabolism
Transcriptional Activation
Transfection
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0006-4971
info:doi/10.1182/blood-2002-09-2851
info:pii/2002-09-2851
info:scp/0038115124
info:pmid/12576336
info:ulb-repo/set/1#28550