Titre:
  • Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.
Auteur:Callewaert, Hanne; Gysemans, Conny A; Ladrière, Laurence; D'Hertog, Wannes; Hagenbrock, Julianna; Overbergh, Lutgart; Eizirik, Decio L.; Mathieu, Chantal
Informations sur la publication:Diabetes, 56, 8, page (2169-2173)
Statut de publication:Publié, 2007
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Alloxan -- pharmacology
Animals
Diabetes Mellitus, Experimental -- chemically induced
Diabetes Mellitus, Experimental -- immunology
Diabetes Mellitus, Experimental -- metabolism
Diabetes Mellitus, Experimental -- pathology
Dose-Response Relationship, Drug
Gene Expression Regulation
Graft Rejection -- immunology
Graft Rejection -- prevention & control
Interleukin-1beta -- metabolism
Islets of Langerhans Transplantation -- immunology
Mice
Mice, Knockout
STAT1 Transcription Factor -- deficiency
STAT1 Transcription Factor -- genetics
STAT1 Transcription Factor -- metabolism
Signal Transduction -- drug effects
Streptozocin -- pharmacology
Survival Rate
Time Factors
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0012-1797
info:doi/10.2337/db07-0052
info:pii/db07-0052
info:scp/34547561721
info:pmid/17473223