par De Bie, Lara ;Roovers, Martine ;Oudjama, Yamina;Wattiez, Ruddy ;Tricot, Catherine ;Stalon, Victor ;Droogmans, Louis ;Bujnicki, Janusz Marek
Référence Journal of bacteriology, 185, 10, page (3238-3243)
Publication Publié, 2003-05
Référence Journal of bacteriology, 185, 10, page (3238-3243)
Publication Publié, 2003-05
Article révisé par les pairs
Résumé : | We cloned, expressed, and purified the Escherichia coli YggH protein and show that it catalyzes the S-adenosyl-L-methionine-dependent formation of N(7)-methylguanosine at position 46 (m(7)G46) in tRNA. Additionally, we generated an E. coli strain with a disrupted yggH gene and show that the mutant strain lacks tRNA (m(7)G46) methyltransferase activity. |