Titre :
  • Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
Auteur : Di Croce, Luciano ; Raker, Veronica A ; Corsaro, Massimo ; Fazi, Francesco ; Fanelli, Mirco ; Faretta, Mario ; Fuks, François ; Lo Coco, Francesco ; Kouzarides, Tony ; Nervi, Clara ; Minucci, Saverio ; Pelicci, Pier Giuseppe
Informations sur la publication : Science, 295, 5557, (page 1079-1082)
Statut de publication : Publié, 2002-02
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Azacitidine -- analogs & derivatives
Azacitidine -- pharmacology
Binding Sites
Cell Differentiation -- drug effects
Cell Line
Cell Nucleus -- metabolism
Cell Transformation, Neoplastic
Cloning, Molecular
CpG Islands
DNA (Cytosine-5-)-Methyltransferase -- metabolism
DNA Methylation
Exons
Gene Expression
Gene Silencing
Histone Deacetylases -- metabolism
Humans
Leukemia, Promyelocytic, Acute -- genetics
Mutation
Neoplasm Proteins -- metabolism
Oncogene Proteins, Fusion -- metabolism
Promoter Regions, Genetic
Receptors, Retinoic Acid -- genetics
Recombinant Fusion Proteins -- metabolism
Transcription Factors -- metabolism
Tretinoin -- pharmacology
Tumor Cells, Cultured
Zinc -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0036-8075 
info:doi/10.1126/science.1065173
info:pii/295/5557/1079
info:pmid/11834837