Titre :
  • Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs
Auteur : Pirot, Pierre ; Naamane, Najib ; Libert, Frédérick ; Magnusson, N. E. ; Orntoft, Torben Falck ; Cardozo, Alessandra K ; Eizirik, Decio L.
Informations sur la publication : Diabetologia, (page 1229-1236)
Statut de publication : Publié, 2007
Sujet CREF : Médecine clinique [biologie clinique]
Mots-clés : Apoptosis
CPA
Cyclopiazonic acid
Diabetes mellitus
Endoplasmic reticulum stress
Insulin
Interleukin-1
Pancreatic beta cells
Mots-clés MeSH : Cell Line
Cell Survival
Cells, Cultured
Endoplasmic Reticulum -- physiology
Gene Expression Profiling
Gene Expression Regulation
Humans
Indoles -- pharmacology
Insulin -- genetics
Insulin-Secreting Cells -- cytology
Insulin-Secreting Cells -- drug effects
Insulin-Secreting Cells -- physiology
Kinetics
Oligonucleotide Array Sequence Analysis
Polymerase Chain Reaction
RNA, Messenger -- metabolism
Stress, Mechanical
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-007-0609-0
info:pmid/17333111
ppi-0005