Titre :
  • Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms
Auteur : Pirot, Pierre ; Eizirik, Decio L. ; Cardozo, Alessandra K
Informations sur la publication : Diabetologia, 49, (page 1229-1236)
Statut de publication : Publié, 2006
Sujet CREF : Médecine clinique [biologie clinique]
Mots-clés : Apoptosis
Endoplasmic reticulum stress
Interferon-γ
Pancreatic beta cells
Type 1 diabetes mellitus
Mots-clés MeSH : Animals
Apoptosis -- drug effects
Calcium -- metabolism
Cell Death -- drug effects
Cell Line
Cell Survival -- drug effects
Endoplasmic Reticulum -- drug effects
Endoplasmic Reticulum -- physiology
Endoplasmic Reticulum -- ultrastructure
Gene Expression Regulation -- drug effects
Gene Expression Regulation -- physiology
Indoles -- pharmacology
Insulin-Secreting Cells -- drug effects
Insulin-Secreting Cells -- physiology
Interferon-gamma -- pharmacology
Interleukin-1 -- pharmacology
Rats
Reverse Transcriptase Polymerase Chain Reaction
Stress, Mechanical
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-006-0214-7
info:pmid/16604358
ppi-0003