par Gevenois, Pierre-Alain ;Zanen, J.;De Maertelaer, Viviane ;De Vuyst, Paul ;Dumortier, Pascal ;Yernault, Jean Claude
Référence Journal of Clinical Pathology, 48, 4, page (318-322)
Publication Publié, 1995
Référence Journal of Clinical Pathology, 48, 4, page (318-322)
Publication Publié, 1995
Article révisé par les pairs
Résumé : | AIMS--To propose a computerised image analysis based method for measuring, on paper mounted lung sections, the area macroscopically occupied by emphysema. METHODS--The study was based on the assessment of 69 lung sections prepared following a modified Gough-Wentworth technique. The results obtained from image analysis, point counting, and panel grading methods were compared, as was the repeatability of image analysis and panel grading. RESULTS--The results from image analysis and from point counting were not significantly different (p = 0.609) and significant quadratic regressions (r = 0.96, p < 0.001) were found between measurements from image analysis and from panel grading, the computerised technique being shown to be the most reproducible. CONCLUSIONS--Image analysis is a valuable and reproducible method to measure the area of lung macroscopically involved by emphysema. |