Titre:
  • TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells.
Auteur:Marroquí, Laura; Dos Santos, Reinaldo Sousa; Fløyel, Tina; Grieco, Fabio Arturo; Santin Gomez, Izortze; Op De Beeck, Anne; Marselli, Lorella; Marchetti, Piero; Pociot, Flemming Michael; Eizirik, Decio L.
Informations sur la publication:Diabetes, 64, 11, page (3808-3817)
Statut de publication:Publié, 2015-11
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Apoptosis -- genetics -- immunology
Cell Line
Cell Survival -- genetics
Chemokine CXCL10 -- genetics -- metabolism
Diabetes Mellitus, Type 1 -- genetics -- metabolism
Genes, MHC Class I -- physiology
Genome-Wide Association Study
Humans
Immunity, Innate -- genetics
Insulin-Secreting Cells -- immunology -- metabolism
Interferon-alpha -- genetics -- metabolism
Phosphorylation
Polymorphism, Single Nucleotide
TYK2 Kinase -- genetics -- metabolism
Langue:Anglais
Identificateurs:urn:issn:0012-1797
info:doi/10.2337/db15-0362
info:pii/db15-0362
info:pmid/26239055