Titre:
  • p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.
Auteur:Litwak, Sara A; Loh, Kim; Stanley, William J; Pappas, Evan G; Wali, Jibran A; Selck, Claudia; Strasser, Andreas; Thomas, Helen H.E.; Gurzov, Esteban Nicolas
Informations sur la publication:Scientific reports, 6, page (23802)
Statut de publication:Publié, 2016-04
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adipose Tissue -- pathology
Animals
Apoptosis Regulatory Proteins -- deficiency -- genetics -- physiology
Body Weight -- physiology
Diet, High-Fat -- adverse effects
Eating -- physiology
Glucose -- metabolism
Glucose Tolerance Test
Homeostasis -- physiology
Insulin -- pharmacology
Insulin Resistance
Leptin -- blood
Liver -- pathology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Obesity -- pathology -- physiopathology
Recombinant Proteins -- pharmacology
Tumor Suppressor Proteins -- deficiency -- genetics -- physiology
Langue:Anglais
Identificateurs:urn:issn:2045-2322
info:doi/10.1038/srep23802
info:pii/srep23802
info:pmid/27033313
PMC4817123