Titre:
  • Lipotoxic Stress Induces Pancreatic Beta-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System.
Auteur:Litwak, Sara A; Wali, Jibran A; Pappas, Evan EG; Saadi, Hamdi; Stanley, William J; Varanasi, Chitra LC; Kay, Thomas W H TW; Thomas, Helen H.E.; Gurzov, Esteban Nicolas
Informations sur la publication:Journal of diabetes research, 2015, page (280615)
Statut de publication:Publié, 2015
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Apoptosis -- drug effects
Cell Line
Cell Survival -- drug effects
Endoplasmic Reticulum Stress -- drug effects
Humans
Insulin-Secreting Cells -- drug effects -- metabolism
Leupeptins -- pharmacology
Mice
Palmitic Acid -- pharmacology
Proteasome Endopeptidase Complex -- metabolism
Proto-Oncogene Proteins c-bcl-2 -- metabolism
Ubiquitin -- metabolism
Ubiquitination -- drug effects
Langue:Anglais
Identificateurs:urn:issn:E231997
info:doi/10.1155/2015/280615
info:pmid/26064977
PMC4438180