Titre:
  • P53 and MITF/Bcl-2 identified as key pathways in the acquired resistance of NRAS-mutant melanoma to MEK inhibition
Auteur:Najem, Ahmad; Krayem, Mohammad; Sales, François; Hussein, Nader; Badran, Bassam; Robert, Caroline; Awada, Ahmad; Journé, Fabrice; Ghanem, Ghanem Elias
Informations sur la publication:European journal of cancer, 83, page (154-165)
Statut de publication:Publié, 2017-09
Sujet CREF:Cancérologie
Mots-clés:Q61NRAS
Bcl-2 inhibition
Drug resistance
MEK inhibition
Melanoma
p53 activation
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0959-8049
info:doi/10.1016/j.ejca.2017.06.033
info:pii/S0959804917310997
info:scp/85025100241
info:pmid/28738256