• Citer

Absorption Spectra and Structure of Barbituric Acid Derivatives as a Function of pH

par Fox, Jack Jeffrey;Shugar, David
Référence Bulletin des Sociétés chimiques belges, 61, 1-2, page (44-63)
Publication Publié, 1952

Article révisé par les pairs

• Détails
• Contenu

Résumé :

Summary.‐ The ultraviolet absorption spectra of several barbituric acid derivatives have been measured and their apparent dissociation constants determined. The variation of the spectra of barbital and its N‐methyl derivatives with pH is shown to be explicable on the basis of ionic dissociation. The spectrum of barbituric acid, in which only two of the three potentially‐dissociable groups are exhibited, is discussed in relation to other spectral characteristics. The sites of enolizations in barbituric acid and barbital and the order in which these ionic equilibria occur as a function of pH are suggested. Copyright © 1952 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim