par Liberale, Gabriel 
;Flamen, Patrick ;Lecocq, Céline ;Garcia, Camilo ;Muylle, Kristoff ;Covas, Angélique ;Deleporte, Amélie;Hendlisz, Alain ;Bouazza, F.;El Nakadi, Issam
Référence Anticancer research, 37, 2, page (929-934)
Publication Publié, 2017
;Flamen, Patrick ;Lecocq, Céline ;Garcia, Camilo ;Muylle, Kristoff ;Covas, Angélique ;Deleporte, Amélie;Hendlisz, Alain ;Bouazza, F.;El Nakadi, Issam Référence Anticancer research, 37, 2, page (929-934)
Publication Publié, 2017
Article révisé par les pairs
| Résumé : | Background/Aim: Neoadjuvant chemotherapy may be administered to patients with peritoneal carcinomatosis (PC) of colorectal cancer (CRC) origin. This study evaluated the performance of 18fluorodeoxyglucose positron-emission tomography (FDG-PET)/computed tomography (CT) in detection of PC from CRC and correlated the most metabolically active quadrant with the most affected peritoneal area determined during surgery. Patients and Methods: This retrospective study compared the performance of FDG-PET/CT for PC diagnosis in 26 patients with CRC with histopathologically-confirmed PC with a control group of 26 patients. An FDG-PET/CT score established for each patient diagnosed with PC was compared with the peritoneal cancer index (PCI) performed during surgery. Results: The sensitivity and specificity of FDG-PET/CT for PC detection were 85% (22/26) and 88% (23/26), respectively. The most scored quadrant by FDGPET/ CT corresponded to the most scored quadrant at surgery in 77.3%. Conclusion: FDG-PET/CT may represent a useful tool for evaluating response to neoadjuvant chemotherapy in patients with PC of CRC origin. |
