Titre :
  • By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization.
Auteur : Iturrioz, Xavier X ; Gerbier, Romain ; Leroux, Vincent ; Alvear-Perez, Rodrigo R ; Maigret, Bernard ; Llorens-Cortes, Catherine C
Informations sur la publication : The Journal of biological chemistry, 285, 42, (page 32627-32637)
Statut de publication : Publié, 2010-10
Sujet CREF : Sciences bio-médicales et agricoles
Sciences exactes et naturelles
Mots-clés MeSH : Amino Acid Sequence
Animals
CHO Cells
Cricetinae
Cricetulus
Cyclic AMP -- metabolism
Humans
Intercellular Signaling Peptides and Proteins -- chemistry -- genetics -- metabolism
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
Phenylalanine -- metabolism
Protein Conformation
Radioligand Assay
Rats
Receptors, G-Protein-Coupled -- genetics -- metabolism
Recombinant Fusion Proteins -- genetics -- metabolism
Tryptophan -- metabolism
Langue :
  • Anglais
Identificateurs : urn:issn:0021-9258 
info:doi/10.1074/jbc.M110.127167
info:pii/M110.127167
info:pmid/20675385
info:pmcid/PMC2952265