Résumé : Inclusive jet, dijet and trijet differential cross sections are measured in neutral current deep-inelastic scattering for exchanged boson virtualities 150 < Q2< 15 000 GeV2using the H1 detector at HERA. The data were taken in the years 2003 to 2007 and correspond to an integrated luminosity of 351 pb−1. Double differential jet cross sections are obtained using a regularised unfolding procedure. They are presented as a function of Q2and the transverse momentum of the jet, Pjet T, and as a function of Q2and the proton’s longitudinal momentum fraction, ξ, carried by the parton participating in the hard interaction. In addition normalised double differential jet cross sections are measured as the ratio of the jet cross sections to the inclusive neutral current cross sections in the respective Q2bins of the jet measurements. Compared to earlier work, the measurements benefit from an improved reconstruction and calibration of the hadronic final state. The cross sections are compared to perturbative QCD calculations in next-to-leading order and are used to determine the running coupling and the value of the strong coupling constant as αs(MZ) = 0.1165 (8)exp(38)pdf, theo.