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Fatal community-acquired ribotype 002 Clostridium difficile bacteremia.

par Dauby, Nicolas ;Libois, Agnès;Van Broeck, J;Delmée, Michel;Vandenberg, Olivier ;Martiny, Delphine
Référence Anaerobe, 44, page (1-2)
Publication Publié, 2017-04-01

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Résumé :

Extra-colonic infections, and especially bacteremia, are infrequent manifestations of Clostridium difficile infection. C. difficile bacteremia is generally health-care associated and polymicrobial. We report the case of a patient on hunger strike that presented a C. difficile colitis and mono-microbial bacteremia on its admission to the hospital. Multilocus variable number tandem repeat analysis of stool and blood isolates indicated clonality. The strain was characterized as a ribotype 002, an emerging ribotype previously associated with high fatality rate. The patient received treatment by intra-venous amoxicillin-clavulanate and oral vancomycin but eventually died on the seventh day of admission with concomitant pneumonia and pulmonary embolism.