par Dumont, Jacques Emile 
;Ermans, André Marie ;Bastenie, Paul Auguste
Référence The Journal of clinical endocrinology and metabolism, 23, 4, page (325-335)
Publication Publié, 1963
;Ermans, André Marie ;Bastenie, Paul Auguste Référence The Journal of clinical endocrinology and metabolism, 23, 4, page (325-335)
Publication Publié, 1963
Article révisé par les pairs
| Résumé : | Thirty-five patients with retarded bodily growth, retarded mental development and typical cretinoid appearance have been studied in the endemic goiter area of the Uele (Congo). These patients, who may thus be called endemic cretins, exhibit clinical, electrocardiographic, radiologic and biological evidence of present hypothyroidism. The severity of the stigmata of cretinism (nanism, imbecility) has been related to the severity of hypothyroidism, as evidenced by retardation of bone maturation, abdominal swelling, umbilical hernia, myxedema and atrophic genitalia. As experimental evidence shows that a clinical picture similar to cretinism can be produced in animals by hypothyroidism, it is concluded that Uele endemic cretinism is mainly due to hypothyroidism. © 1963 by The Endocrine Society. |
