Résumé : The electrochemical behavior of Tizanidine has been studied using dc, ac, and pulse polarographic techniques. Reduction of the compound occurs through an electrochemical mechanism involving a six‐electron transfer. Autoinhibition of the process resulting from the adsorption of species affects the reduction rate constants. At the electrode surface, adsorption proceeds through a competition between the oxidized and reduced forms. Copyright © 1991 VCH Publishers, Inc.