par Brachet, Jean 
Référence Development, growth & differentiation, 18, 3, page (235-243)
Publication Publié, 1976
Référence Development, growth & differentiation, 18, 3, page (235-243)
Publication Publié, 1976
Article révisé par les pairs
| Résumé : | After a review of our present knowledge about the effects of proteases and protease inhibitors on cell growth and egg fertilization, the results of experiments where sea urchin and amphibian eggs were treated with two protease inhibitors (TPCK, TLCK) are described. Cleavage was hardly affected, but gastrulation quickly stopped or was incomplete. The morphogenetic abnormalities which follow can be explained by abnormal gastrulation and other factors: persistence of remnants of the fertilization membrane in sea urchin larvae and dissociation of the ectoderm cells in Xenopus embryos. Copyright © 1976, Wiley Blackwell. All rights reserved |
