Titre:
  • LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins.
Auteur:Planinc, Ana; Dejaegher, Bieke; Vander Heyden, Yvan; Viaene, Johan; Van Praet, Serge; Rappez, Florence; Van Antwerpen, Pierre; Delporte, Cédric
Informations sur la publication:Analytical and Bioanalytical Chemistry
Statut de publication:Publié, 2016-06
Sujet CREF:Sciences bio-médicales et agricoles
Sciences pharmaceutiques
Analyse et contrôle pharmaceutique
Chimie analytique
Mots-clés:High-resolution mass spectrometry (HRMS)
Hydrophilic interaction liquid chromatography (HILIC)
N-Glycans
Principal component analysis (PCA)
Soft independent modelling by class analogy (SIMCA)
Therapeutic glycoproteins
Langue:Anglais
Identificateurs:urn:issn:1618-2642
info:doi/10.1007/s00216-016-9683-9
info:pii/10.1007/s00216-016-9683-9
info:pmid/27287011
info:ulb-repo/set/1#43305