Titre :
  • LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins.
Auteur : Planinc, Ana ; Dejaegher, Bieke ; Vander Heyden, Yvan ; Viaene, Johan ; Van Praet, Serge ; Rappez, Florence ; Van Antwerpen, Pierre ; Delporte, Cédric
Informations sur la publication : Analytical and Bioanalytical Chemistry
Statut de publication : Publié, 2016-06
Sujet CREF : Sciences bio-médicales et agricoles
Sciences pharmaceutiques
Analyse et contrôle pharmaceutique
Chimie analytique
Mots-clés : High-resolution mass spectrometry (HRMS)
Hydrophilic interaction liquid chromatography (HILIC)
N-Glycans
Principal component analysis (PCA)
Soft independent modelling by class analogy (SIMCA)
Therapeutic glycoproteins
Langue :
  • Anglais
Identificateurs : urn:issn:1618-2642 
info:doi/10.1007/s00216-016-9683-9
info:pii/10.1007/s00216-016-9683-9
info:pmid/27287011
info:ulb-repo/set/1#43305