par De Backer, Daniel 
Editeur scientifique Telo, Mario
Référence Paradise Lost and the Cosmological Revolution, Cambridge University Press, New York, page (180-185)
Publication Publié, 2014-01
Editeur scientifique Telo, Mario
Référence Paradise Lost and the Cosmological Revolution, Cambridge University Press, New York, page (180-185)
Publication Publié, 2014-01
Partie d'ouvrage collectif
| Résumé : | Introduction Optimization of tissue perfusion is one of the primary goals of perioperative optimization and resuscitation of the critically ill. Adequacy of tissue perfusion is often assumed from systemic measures including blood pressure, cardiac output, and venous oxygen saturation. However, microcirculatory alterations may occur even when global hemodynamic variables are within targets. Alterations in microcirculatory blood flow have been identified in several disease processes and are associated with outcome. Microcirculatory alterations also occur in the perioperative period. In patients submitted to high-risk surgery, the severity of the alterations was associated with development of perioperative complications. Assessment of the microcirculation may thus be desirable. The incidence and relevance of microcirculatory alterations have been reviewed in detail in Chapter 8. The characteristics of these microvascular alterations have profound implications for monitoring. These are characterized by a decrease in capillary density, but also and more importantly, by heterogeneity in perfusion, with perfused capillaries in close vicinity of non-perfused capillaries. |
