Article révisé par les pairs
| Résumé : | There are now several non intrusive techniques (infrared and very high frequency) allowing quantitative objective measurements of inflammatory reactions in man to be made. A radioisotopic technique (99mTcFi) is presented allowing characterisation of established and early RA lesions in a more specific way than by previously available techniques; this technique appears to lend itself to quantitative measurements. The ratio of synovial to plasma β2m apparently allows differentiation between RA and microcristalline arthritis. β2m levels in blood and synovial fluid allow an estimation of RA disease activity in absence of other causes of increased levels (renal disease, pregnancy and/or malignancy); they corroborate hydroxyproline levels in RA synovial fluid. Synovial levels give a tentative index of tissue destruction in RA and microcristalline arthritis. |
