par Nguyen, Anh Tho ;Duez, Pierre
Editeur scientifique Telo, Mario
Référence New Developments in Medicinal Chemistry, Nova Science Publishers, Inc., New York, page (65-80)
Publication Publié, 2009
Partie d'ouvrage collectif
Résumé : Although there have been large improvements in cancer treatment over the last twenty years, the lack of cancer chemotherapeutic drugs is still a major cause of death in this century. Medicinal plants play an important role in the treatment of cancer by offering unique active drugs or their templates for clinical uses, as exemplified by paclitaxel (Taxol®), vinca alkaloids (vincristine, vinblastine), and flavopiridol. The strategies for developing anticancer agents from medicinal plants have changed in the last decade for a number of reasons, including advances in technology, changes in the plant selection mode and biological activity testing. This review reflects and discusses the newest methods applied for searching anticancer agents from medicinal plants including plant selection and extraction, the active principle isolation, structure elucidation and biological testing. This review reflects and discusses the newest methods applied for searching anticancer agents from medicinal plants including plant selection and extraction, the active principle isolation, structure elucidation and biological testing. © 2009 Nova Science Publishers, Inc. All rights reserved.