Article révisé par les pairs
Résumé : Studies about hemodynamics in isolated interventricular septal defects show that from the physiological point of view, these congenital malformations represent two different types with transitory forms. The first type is characterized by a small interventricular arteriovenous shunt: the X-ray aspect of the heart is normal or only slightlv modified: the axis of the electrocardiogram is normal or slightly deviated to the left or to the right. In the second type, there is a very important arterio-venous shunt. Such a shunt is responsible for a marked increase of the pulmonary output; the pressures in the right ventricle and in the pulmonary artery are usually normal, the X-ray shows a hypertrophy of the right cavities and a dilatation of the pulmonary artery and its branches; there is a right axis deviation and fairly often trouble in the intra-cardiac conduction. Clinical aspects and prognosis of isolated interventricular septal defects depend essentially on the importance of the arterio-venous shunt existing in this congenital heart disease. © 1952 S. Karger AG, Basel.