Titre:
  • Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial.
Auteur:Westphal, Manfred; Ylä-Herttuala, Seppo Pasi Antero S.; Martin, John; Warnke, Peter; Menei, Philippe P; Eckland, David D; Kinley, Judith J; Kay, Richard; Ram, Zvi; De Witte, Olivier
Informations sur la publication:Lancet oncology, 14, 9, page (823-833)
Statut de publication:Publié, 2013-08
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adenoviridae -- genetics
Adolescent
Adult
Aged
Antiviral Agents -- therapeutic use
Brain Neoplasms -- genetics -- mortality -- pathology -- therapy
Combined Modality Therapy
Female
Follow-Up Studies
Ganciclovir -- therapeutic use
Genetic Therapy
Glioma -- genetics -- mortality -- pathology -- therapy
Humans
Male
Middle Aged
Neoplasm Grading
Prognosis
Survival Rate
Thymidine Kinase -- therapeutic use
Young Adult
Langue:Anglais
Identificateurs:urn:issn:1470-2045
info:doi/10.1016/S1470-2045(13)70274-2
info:pii/S1470-2045(13)70274-2
info:pmid/23850491