Titre :
  • PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.
Auteur : Moore, Fabrice ; Luis Colli, MAIKEL ; Cnop, Miriam ; Igoillo Esteve, Mariana ; Cardozo, Alessandra K ; Andrade Da Cunha, Daniel ; Bugliani, Marco ; Marchetti, Piero ; Laks Eizirik, Décio
Informations sur la publication : Diabetes, 58, 6, (page 1283-1291)
Statut de publication : Publié, 2009-06
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Aged
Animals
Apoptosis
Cell Death
Cell Line
Cell Survival -- drug effects
Chromosome Mapping
Diabetes Mellitus, Type 1 -- genetics
Genetic Predisposition to Disease
Humans
Insulin-Secreting Cells -- cytology -- drug effects -- physiology
Interferon-gamma -- adverse effects
Interleukin-1beta -- pharmacology
Male
Middle Aged
Nitric Oxide -- metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 2 -- genetics
RNA, Messenger -- genetics
RNA, Small Interfering -- genetics
Rats
Rats, Wistar
Recombinant Proteins -- pharmacology
Tissue Donors
Langue :
  • Anglais
Identificateurs : urn:issn:0012-1797 
info:doi/10.2337/db08-1510
info:pii/db08-1510
info:pmid/19336676
info:pmcid/PMC2682688