Titre:
  • PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.
Auteur:Moore, Fabrice; Luis Colli, MAIKEL; Cnop, Miriam; Igoillo Esteve, Mariana; Cardozo, Alessandra K; Andrade Da Cunha, Daniel; Bugliani, Marco; Marchetti, Piero; Eizirik, Decio
Informations sur la publication:Diabetes, 58, 6, page (1283-1291)
Statut de publication:Publié, 2009-06
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Aged
Animals
Apoptosis
Cell Death
Cell Line
Cell Survival -- drug effects
Chromosome Mapping
Diabetes Mellitus, Type 1 -- genetics
Genetic Predisposition to Disease
Humans
Insulin-Secreting Cells -- cytology -- drug effects -- physiology
Interferon-gamma -- adverse effects
Interleukin-1beta -- pharmacology
Male
Middle Aged
Nitric Oxide -- metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 2 -- genetics
RNA, Messenger -- genetics
RNA, Small Interfering -- genetics
Rats
Rats, Wistar
Recombinant Proteins -- pharmacology
Tissue Donors
Langue:Anglais
Identificateurs:urn:issn:0012-1797
info:doi/10.2337/db08-1510
info:pii/db08-1510
info:pmid/19336676
PMC2682688