Titre :
  • Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
Auteur : Andrade Da Cunha, Daniel ; Ladrière, Laurence ; Ortis, Fernanda ; Igoillo Esteve, Mariana ; Gurzov, Esteban Nicolas ; Lupi, Roberto ; Marchetti, Piero ; Eizirik, Decio ; Cnop, Miriam
Informations sur la publication : Diabetes, 58, 12, (page 2851-2862)
Statut de publication : Publié, 2009-12
Sujet CREF : Enseignement des sciences
Biologie
Biologie moléculaire
Biologie cellulaire
Biologie générale
Diabétologie
Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Antigens, Differentiation -- metabolism
Apoptosis
Blotting, Western
Cell Survival
Colforsin -- pharmacology
DNA-Binding Proteins -- metabolism
Diabetes Mellitus, Type 2 -- metabolism -- prevention & control
Endoplasmic Reticulum -- metabolism
Glucagon-Like Peptide 1 -- agonists -- metabolism
Heat-Shock Proteins -- genetics -- metabolism
Hypoglycemic Agents -- pharmacology
Insulin-Secreting Cells -- metabolism
Lipid Metabolism -- drug effects
Male
Peptides -- pharmacology
Polymerase Chain Reaction
Proto-Oncogene Proteins -- metabolism
Proto-Oncogene Proteins c-jun -- genetics -- metabolism
RNA Interference
Rats
Rats, Wistar
Receptors, Glucagon -- metabolism
Transcription Factors -- metabolism
Up-Regulation
Venoms -- pharmacology
Langue :
  • Anglais
Identificateurs : urn:issn:0012-1797 
info:doi/10.2337/db09-0685
info:pii/db09-0685
info:pmid/19720788
info:pmcid/PMC2780890