Titre :
  • Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Auteur : Andrade Da Cunha, Daniel ; Igoillo Esteve, Mariana ; Gurzov, Esteban Nicolas ; Germano, Carla M ; Naamane, Najib ; Marhfour, Ihsane ; Fukaya, Makiko ; Vanderwinden, Jean-Marie ; Gysemans, Conny ; Mathieu, Chantal ; Marselli, Lorella ; Marchetti, Piero ; Harding, Heather HP ; Ron, David D ; Eizirik, Decio ; Cnop, Miriam
Informations sur la publication : Diabetes, 61, 11, (page 2763-2775)
Statut de publication : Publié, 2012-11
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Aged
Animals
Apoptosis
Apoptosis Regulatory Proteins -- antagonists & inhibitors -- genetics -- metabolism
Cell Line
Cells, Cultured
Endoplasmic Reticulum Stress
Gene Expression Profiling
Humans
Insulin-Secreting Cells -- cytology -- metabolism
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Mitochondria -- metabolism
Palmitic Acid -- adverse effects
Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism
RNA Interference
RNA, Messenger -- metabolism
RNA, Small Interfering
Rats
Langue :
  • Anglais
Identificateurs : urn:issn:0012-1797 
info:doi/10.2337/db12-0123
info:pii/db12-0123
info:pmid/22773666
info:pmcid/PMC3478544