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Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human beta-cell apoptosis.

par Andrade Da Cunha, Daniel ;Igoillo Esteve, Mariana ;Gurzov, Esteban Nicolas ;Germano, Carla Maria Ramos C.M.;Naamane, Najib ;Marhfour, Ihsane ;Fukaya, Makiko ;Vanderwinden, Jean-Marie ;Gysemans, Conny;Mathieu, Chantal;Marselli, Lorella;Marchetti, Piero;Harding, Heather HP;Ron, David;Eizirik, Decio ;Cnop, Miriam
Référence Diabetes (New York, N.Y.), 61, 11, page (2763-2775)
Publication Publié, 2012-11

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Titre:	Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human beta-cell apoptosis.
Auteur:	Andrade Da Cunha, Daniel; Igoillo Esteve, Mariana; Gurzov, Esteban Nicolas; Germano, Carla Maria Ramos C.M.; Naamane, Najib; Marhfour, Ihsane; Fukaya, Makiko; Vanderwinden, Jean-Marie; Gysemans, Conny; Mathieu, Chantal; Marselli, Lorella; Marchetti, Piero; Harding, Heather HP; Ron, David; Eizirik, Decio; Cnop, Miriam
Informations sur la publication:	Diabetes (New York, N.Y.), 61, 11, page (2763-2775)
Statut de publication:	Publié, 2012-11
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Aged
	Animals
	Apoptosis
	Apoptosis Regulatory Proteins -- antagonists & inhibitors -- genetics -- metabolism
	Cell Line
	Cells, Cultured
	Endoplasmic Reticulum Stress
	Gene Expression Profiling
	Humans
	Insulin-Secreting Cells -- cytology -- metabolism
	Male
	Mice
	Mice, Inbred C57BL
	Mice, Knockout
	Middle Aged
	Mitochondria -- metabolism
	Palmitic Acid -- adverse effects
	Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism
	RNA Interference
	RNA, Messenger -- metabolism
	RNA, Small Interfering
	Rats
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db12-0123
	info:pii/db12-0123
	info:pmid/22773666
	PMC3478544