par Doyen, Matthieu ;Goole, Jonathan ;Bartik, Kristin ;Bruylants, Gilles
Référence Journal of colloid and interface science, 464, page (160-166)
Publication Publié, 2015-11-12
Article révisé par les pairs
Résumé : Gold colloids are the object of many studies as they are reported to have potential biological sensing, imaging and drug de-livery applications. In the presence of certain amino acids the aggregation of the gold nanoparticles into linear structures is observed, as highlighted by the appearance of a second plasmon band in the UV-Vis spectra of the colloid. The mechanism behind this phenomenon is still under debate. In order to help elucidate this issue, the interaction between gold colloids and different amino acids, modified amino acids and molecules mimicking their side-chain was monitored by UV-Vis absorp-tion, DLS and TEM. The results show that phenomenon can be rationalized in terms of the Diffusion Limited Colloid Ag-gregation (DLCA) model which gives rise to the fractal aggregation colloids. The global charge of the compound, which in-fluences the ionic strength of the solution, and the ease with which the compound can interact with the GNPs and affect their surface potential, are, the two parameters which control the DLCA regime. Calculations based on the Derjaguin, Lan-dau, Verwey and Overbeek (DLVO) theory confirm all the experimental observations.