Résumé : In the first holographic bubble chamber experiment - the HOBC experiment - we have accumulated a total of 40000 holograms with particle interactions. We have determined the total charm pair cross section in pN collisions to be 23.3-7.7+10 μb and 3.6-1.7+2.3 μb for 360 and 200 GeV/c incident protons respectively. We have assumed a linear dependence of the cross section on the atomic number of the target. This experiment has demonstrated the feasibility of holographic recording in small bubble chambers. Assuming that the charm cross section can be described by the standard QCD factorized expression with gluon fusion and quark-antiquark annihilation, we have used our measured charm cross sections with other measurements to determine the effective charmed quark mass to be 1.8-0.35+0.25 GeV/c2. The K factor, which describes the importance of the higher order corrections, is calculated to be 9.8-6.9+12.5 (See noted added in proof.) © 1987 Springer-Verlag.