par Yourassowsky, Eugène 
;Schoutens, ELISABETH;Vanderlinden, M P;Prudhomme, M.R.
Référence Infection, 3, 1, page (15-18)
Publication Publié, 1975-03
;Schoutens, ELISABETH;Vanderlinden, M P;Prudhomme, M.R.Référence Infection, 3, 1, page (15-18)
Publication Publié, 1975-03
Article révisé par les pairs
| Résumé : | A total of 100 clinical isolates of Haemophilus were tested for susceptibility to 25 antibiotics. The activity of the five penicillins tested, including penicillin G, was good, almost all strains being inhibited by 6.25 μg/ml of the compounds. Erythromcyin and clindamycin showed similar activity: at 6.25 μg/ml, 100% of the strains were inhibited by erythromycin and 96% were inhibited by clindamycin; in contrast, oleandomycin and lincomycin were less inhibitory, with most strains being resistant to 6.25 μg/ml of these two drugs. MIC's of chloramphenicol and thiamphenicol ranged from 0.1-1.56 μg/ml with most strains inhibited by 0.78 μg/ml. Aminoglycosides and antibiotics belonging to the tetracycline group showed good inhibitory effect with the majority of the strains being inhibited by 3.12 μg/ml. Among the cephalosporins studied, cephradine and cephalexin were considerably less active than other members of this group. Cephapirin was the most active. This study suggests that prediction of the susceptibility of Haemophilus strains to cephalosporins, on the basis of one drug of this group tested alone, is likely to be hazardous. © 1975 Verlagsgesellschaft Otto Spatz. |
