par Fumagalli, Gaia;Passarella, Daniele;Mazza, Davide;Christodoulou, Michael M.S.;Damia, Giovanna;Ricci, Francesca;Perdicchia, Dario;Stella, Barbara;Dosio, Franco;Sotiropoulou, Panagiota
Référence ChemPlusChem, 80, 9, page (1380-1383)
Publication Publié, 2015-09
Référence ChemPlusChem, 80, 9, page (1380-1383)
Publication Publié, 2015-09
Article révisé par les pairs
Résumé : | Cyclopamine- and paclitaxel-containing hetero-nanoparticles generated by self-assembly show combined efficacy in the treatment of three different cancer cell lines. The use of ternary combination with the addition of a dye-squalene conjugate secured the obtainment of fluorescent nanoparticles that permitted the observation of the cellular internalization by confocal microscopy and super-resolution dSTORM (direct stochastic optical reconstruction microscopy). |