par Kennes, Bernard ;Dumont, Isabelle ;Brohée, Dany ;Hubert, Claude ;Neve, Pierre
Référence Gerontology, 29, 5, page (305-310)
Publication Publié, 1983
Référence Gerontology, 29, 5, page (305-310)
Publication Publié, 1983
Article révisé par les pairs
Résumé : | Both ageing and vitamin C (VC) deficiency result in immune defect. Since low serum and tissue levels of VC are found in the elderly, we have in a placebo-controlled study, tested the effect of VC supplements (500 mg/day i.m. for 1 month) on various immune parameters. Indeed, VC enhances the proliferative response of T lymphocytes in vitro, and the tuberculin skin hypersensitivity in vivo. Neither the serum concentrations of IgA, IgG and IgM, nor the proportion of E-rosette-forming cells were modified. No significant change was observed in the placebo-treated group. © 1983 S. Karger AG, Basel. |