• Citer

Multi-marker detection approach for improving breast cancer treatment tailoring

par Desmedt, Christine
Promoteur Piccart-Gebhart, Martine ;Sotiriou, Christos
Publication Non publié, 2008-08-27

Thèse de doctorat

• Accès en ligne
• Détails
• Contenu
• Statistiques

Résumé :

the majority of patients with early breast cancer receive some form of systemic adjuvant therapy (chemo-, endocrine, and/or targeted therapy). Despite the increase in adjuvant therapy prescription, little progress has been made with respect to assisting oncologists to determine which breast cancer patients, particularly those deemed at “lower risk” of relapse, require chemotherapy or other systemic therapy and which women can safely be treated with loco-regional treatment alone. For these reasons, the identification of prognostic and predictive markers that will assist the clinician in selecting the most suitable form of medical therapy has become very high priority as well as a real challenge in translational research. \