par Flici, O;Tadjerouni, A.;Robyn, Claude 
Référence Journal de gynécologie obstétrique et biologie de la reproduction, 12, 6, page (579-582)
Publication Publié, 1983
Référence Journal de gynécologie obstétrique et biologie de la reproduction, 12, 6, page (579-582)
Publication Publié, 1983
Article révisé par les pairs
| Résumé : | Gestational trophoblastic tumours include the complete hydatidiform mole (classical) and partial mole in the fetus), invasive mole and choriocarcinoma. Genetically, trophoblastic tumours can arise in different ways: they can be derived from normal zygotes with the maternal and paternal haplotype (normal pregnancy), or from a triploid zygote (partial mole) or from an XX zygote possessing only a duplicated male haplotype and no maternal contribution (complete mole). The low malignancy rate in partial mole (2.4%) compared to the complete mole (10 to 20%) remains a mystery. Further analysis of the genetics of these tumours may well contribute to the understanding of the process of carcinogenesis. |
