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Nosocomial gram-negative bacillary infections in compromised hosts: considerations on prevention and therapy

par Klastersky, Jean
Référence British Journal of Clinical Practice, 42, SUPPL. 57, page (3-10)
Publication Publié, 1988

Article révisé par les pairs

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Résumé :

Compromised patients are predisposed to the acquisition of resistant Gram-negative bacilli from the hospital environment. Infections caused by Gram-positive organisms are becoming more frequent, and this increase is obviously related to the extensive use of in-dwelling intravenous (IV) catheters. In compromised hosts, Gram-negative and Gram-positive infections are almost always nosocomial, being a result of the severity of the underlying disease and frequent and/or prolonged hospitalisation. Careful handwashing by hospital personnel, low microbial diets and careful attention to IV devices can significantly minimise the colonisation phenomenon in hospitalised compromised patients. The level of colonisation by Gram-negative bacilli can also be reduced in these patients by the oral administration of effective antibiotics.