par Song, Micheline
Référence Revue médicale de Bruxelles, 15, 4, page (155-157)
Publication Publié, 1994
Article révisé par les pairs
Résumé : Itching is the predominant symptom of inflammatory skin diseases. Present evidence indicates that histamine and unidentified peptides mediate itching. No evidence is available that lymphokins or cytokines play a direct role as itch mediators. Prostaglandins serve an important synergistic function in itching. Evidence points to a role for opioid peptides of the central nervous system in the perception of itch and as direct mediators. Pruritus may be a prominent symptom in uraemia, biliary obstruction, atopic dermatitis and neoplasia.