par Bieva, Cl;Bernard, Roland ;Putzeys, G.
Référence Annales de Cardiologie et d'Angeiologie, 29, 4, page (303-307)
Publication Publié, 1980
Article révisé par les pairs
Résumé : After determination of normal values of myoglobinemia (below 60 ng/ml) in a large population (329 subjects, 40 to 55 year old), sensitivity and specificity of this test were investigated in the setting of acute myocardial infarction (133 cases). Sensitivity showed clearly to be 100% and the early myoglobinemia rise makes it one of the first quantified biological markers. However, abnormal myoglobin levels are found in several clinical syndromes suggestive of myocardial infarction, or associated with muscular trauma, as after some technical procedures (left heart catheterization, coronarography, electric countershock, intramuscular injection). All these conditions should be taken into account when interpreting the myoglobin results. Nevertheless, myoglobinemia assay is a useful means to early detect the presence of acute myocardial infarction. The definite diagnosis must be assessed later by specific enzymes determination (CK-MB).