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Hemodynamic effects of parenteral and oral mexiletine

par Renard, Marc ;De Hemptinne, Jean ;Gillet, J. M.;Bernard, Roland
Référence Langenbecks Archiv für Chirurgie, 353, 1, page (75-80)
Publication Publié, 1980

Article révisé par les pairs

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Résumé :

Intravenous mexiletine (250 mg in 10 min) given to patients at the acute stage of a myocardial infarction was responsible for a mild decrease of the left ventricular function; two of our patients presented bradycardia with hypotension, immediately corrected by atropine (i.v.). Adverse hemodynamic effects are seldom reported after oral administration.