par Mendlewicz, Julien 
;Sevy, Serge
Référence L'Encéphale, 11, 6, page (255-259)
Publication Publié, 1985
;Sevy, SergeRéférence L'Encéphale, 11, 6, page (255-259)
Publication Publié, 1985
Article révisé par les pairs
| Résumé : | The widespread use of benzodiazepines has led the authors to review their pharmacological and clinical aspects. On a molecular level, the benzodiazepines have an effect on receptors in relation with the GABA system. Presently, endogenous ligand(s) to these receptors have not yet been fully demonstrated. The main benzodiazepines are also compared for their kinetics, which is a function of absorption, metabolisation and various factors such as binding to the receptor, age, hepatic and renal disorders. These pharmacological studies have clinical implications. The authors finally briefly review the clinical indications of the benzodiazepines. |
