par Regnier, René
Référence Journal belge de radiologie, 62, 2, page (187-193)
Publication Publié, 1979
Article révisé par les pairs
Résumé : In the period 1965-1974, the Institut Bordet treated 35 patients suffering from osteogenic sarcoma. Radiotherapy was used in 23 cases: these treatments invariably consisted of high level radiation. An analysis of the results of these 23 treatments confirms the conclusion drawn from a study of the results of patients treated by 200 kV X-rays up to 1964. If a tumour irradiated at a dosage of 6000-7000 rads is left in situ for 3-6 months, the chances of survival of patients are not compromised. Radiotherapy can, only in exceptional cases, definitively eliminate such tumours. Moreover, it appears that in respect of standard therapy no significant progress in local treatment has resulted from the use of higher dosages, within the limits of tolerance of healthy tissues to ionising radiation even at high levels. The optimism generated by various recent articles that such progress could result from the use of unusual fractionation, radiosensitivity inducing agents or associated treatments, is discussed in the light of this limited experience. The importance of perfecting efficacious adjuvant treatment for the irradiation of micrometastases, in particular those of the lung, is equally stressed.