par Gratia, Jean-Pierre
Référence Molecular & general genetics : MGG, 124, 2, page (157-166)
Publication Publié, 1973-06
Article révisé par les pairs
Résumé : Bacteriophage φ{symbol}γ, produced by Escherichia coli, is a novel type of specialized transducer for the tryptophan region. Its transducing ability strikingly differs from other transducing systems. A long segment of the host-chromosome is picked up at a relatively high frequency upon either induction or lytic development of the phage. Even in absence of stable prophage integration, such segment has its origin at the phage attachment site. Transduced markers are incorporated by exchange crossing-over (rec dependent mechanism), without formation of heterogenotes. The gene pickup is dependent on a non-essential function of the φ{symbol}γ genome. © 1973 Springer-Verlag.